01964    a2200325   4500001001100000005001700011008004100028020001800069037003600087040000700123041000800130072001500138072001500153072001300168072001300181072002100194072002100215072002100236072002100257072002100278100001900299245002900318250000600347260002400353300001000377520117500387700002101562700002601583700002901609113811396420250317100406.0250312042017xx        58           eng    a9781138113961  bTaylor & FranciscGBP 74.99fBB  a01  aeng7 aPSB2thema7 aPSF2thema7 aPSB2bic7 aPSF2bic7 aMED0080002bisac7 aSCI0170002bisac7 aSCI0430002bisac7 aSCI0860002bisac7 a612.015772bisac1 aEric J. Murphy10aLipid-Mediated Signaling  a1  bCRC Pressc20170912  a452 p  bAs the highly anticipated update to Lipid Second Messengers (CRC Press, 1999), Lipid-Mediating Signaling is a current and comprehensive overview of research methods used in lipid-mediated signal transduction. Pioneering experts provide a much-needed distillation of a decade’s worth of advances in research techniques that are pertinent in understanding how lipid-mediated signal transduction ties to pathologic disorders. Part I describes methods used to identify activities of and assay the expression of different enzymes involved in lipid-mediated signaling. Part II highlights the use of mass spectrometry to ascertain the lipid content in various systems. Part III contains two chapters devoted to techniques used to determine the role of lipids in the activation of gene transcription. Part IV rounds out the book’s solid coverage by focusing on methods used to assess fatty acid uptake and metabolism. Lipid-Mediating Signaling is an unrivaled reference for this rapidly expanding, yet resource-limited field, and it is a valuable resource for for cell biologists, biochemists, and pharmacologists, as well as for researchers studying signaling transduction.1 aEric Murphy4B011 aThad Rosenberger4B011 aThad A. Rosenberger4B01