01991 a2200337 4500 1138113964 20250317100406.0 250312042017xx 58 eng 9781138113961 Taylor & Francis GBP 74.99 BB 01 eng PSB thema PSF thema PSB bic PSF bic MED008000 bisac SCI017000 bisac SCI043000 bisac SCI086000 bisac 612.01577 bisac Eric J. Murphy Lipid-Mediated Signaling 1 CRC Press 20170912 452 p As the highly anticipated update to Lipid Second Messengers (CRC Press, 1999), Lipid-Mediating Signaling is a current and comprehensive overview of research methods used in lipid-mediated signal transduction. Pioneering experts provide a much-needed distillation of a decade’s worth of advances in research techniques that are pertinent in understanding how lipid-mediated signal transduction ties to pathologic disorders. Part I describes methods used to identify activities of and assay the expression of different enzymes involved in lipid-mediated signaling. Part II highlights the use of mass spectrometry to ascertain the lipid content in various systems. Part III contains two chapters devoted to techniques used to determine the role of lipids in the activation of gene transcription. Part IV rounds out the book’s solid coverage by focusing on methods used to assess fatty acid uptake and metabolism. Lipid-Mediating Signaling is an unrivaled reference for this rapidly expanding, yet resource-limited field, and it is a valuable resource for for cell biologists, biochemists, and pharmacologists, as well as for researchers studying signaling transduction. Eric Murphy B01 Thad Rosenberger B01 Thad A. Rosenberger B01 1770 1770