01354 a2200301 4500001001100000005001700011008004200028020001800070037003600088040000700124041000800131072001400139072001600153072001200169072001400181072002100195072002100216072001800237100002500255245007900280250000600359260002400365300001000389520058700399700002800986700002301014999001501037142004437020250317100410.0250312042007xx 227 eng  a9781420044379 bTaylor & FranciscGBP 82.99fBB a01 aeng7 aPS2thema7 aTDCW2thema7 aPS2bic7 aTDCW2bic7 aMED0710002bisac7 aSCI0130002bisac7 a615.192bisac1 aDaan J. A. Crommelin10aPharmaceutical BiotechnologybFundamentals and Applications, Third Edition a3 bCRC Pressc20071030 a512 p bCompletely revised text that reflects to emergent trends and cutting-edge advances in pharmaceutical biotechnology, this Third Edition provides a well-balanced framework for understanding every major aspect of pharmaceutical biotechnology, including drug development, production, dosage forms, administration, and therapeutic developments. New chapters cover evolving areas regarding biopharmaceuticals, including oligonucleotides, siRNA and various monoclonal antibodies, immunogenicity, gene therapy, and the regulatory issues factoring into the biopharmaceutical approval process1 aRobert D. Sindelar4B011 aBernd Meibohm4B01 c2277d2277