000 02323 a2200325 4500
001 1138116688
005 20250317100351.0
008 250312042017xx 70 eng
020 _a9781138116689
037 _bTaylor & Francis
_cGBP 74.99
_fBB
040 _a01
041 _aeng
072 7 _aPNF
_2thema
072 7 _aMKG
_2thema
072 7 _aPNN
_2thema
072 7 _aPNF
_2bic
072 7 _aMMG
_2bic
072 7 _aPNN
_2bic
072 7 _aSCI013000
_2bisac
072 7 _aSCI013010
_2bisac
072 7 _aSCI013040
_2bisac
072 7 _a615.19
_2bisac
100 1 _aBing Yan
245 1 0 _aAnalytical Methods in Combinatorial Chemistry
250 _a2
260 _bCRC Press
_c20170614
300 _a238 p
520 _bSince the publication of the benchmark first edition of this book, chemical library and combinatorial chemistry methods have developed into mature technologies. There have also been significant shifts in emphasis in combinatorial synthesis. Reflecting the growth in the field and the heightened focus on select areas, Analytical Methods in Combinatorial Chemistry, Second Edition updates a classic text and captures the current state of these technologies. Written by leaders in the field, this second edition includes several enhancements. A chapter on high-throughput analytical methods and informatics reflects the demand for quality control of library members. A new chapter focuses on high-throughput purification methods. All chapters have been updated with new data. Topics discussed in this second edition include: Properties of solid-phase samples, analytical studies targeted to understand these properties, and resin swelling Fourier Transform Infrared techniques On-support mass spectrometry and nuclear magnetic resonance methods used in the reaction optimization stage Combinatorial library analysis using spectrophotometric, fluorometric, and other methods Quality control of combinatorial libraries High-throughput purification methods Future directions and analytical challenges The coming decade is sure to usher in a new wave of progress in this critical field. This volume provides not only an analysis of the recent developments in analytical methods, technologies and applications; it also provides a window on future possibilities.
700 1 _aBin Zhang
_4A01
999 _c119
_d119