MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03551nam a2200409 a 4500 |
| 001 - CONTROL NUMBER |
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| control field |
00012595 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
WSP |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20250414083509.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
|---|
| fixed length control field |
cr |nu|||unuuu |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
230815s2024 si ob 001 0 eng d |
| 010 ## - LIBRARY OF CONGRESS CONTROL NUMBER |
|---|
| LC control number |
2023016775 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9789811248665 |
| Qualifying information |
(ebook) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9811248664 |
| Qualifying information |
(ebook) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| Canceled/invalid ISBN |
9789811248658 |
| Qualifying information |
(hbk.) |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
WSPC |
| Language of cataloging |
eng |
| Transcribing agency |
WSPC |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
RC268.4 |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
SCI |
| Subject category code subdivision |
007000 |
| Source |
bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
MED |
| Subject category code subdivision |
062000 |
| Source |
bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
SCI |
| Subject category code subdivision |
017000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
616.99/4042 |
| Edition information |
23 |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
MAIN |
| 245 00 - TITLE STATEMENT |
|---|
| Title |
RNA-based mechanisms in cancer |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc. |
editors, Gary Brewer, Gerald M Wilson. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Singapore : |
| Name of publisher, distributor, etc. |
World Scientific, |
| Date of publication, distribution, etc. |
c2024. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
1 online resource (.xv, 496 p.) |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc. note |
Includes bibliographical references and index. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Introduction to RNA and cancer -- Aberrant RNA splicing and therapeutic reprogramming in cancer -- Alternative 3'-RNA processing in cancer -- Tandem CCCH zinc finger RNA-binding proteins and their roles in tumor progression -- Roles of the Hu/ELAV family of mRNA-stabilizing proteins in tumor development -- Pro- and anti-tumorigenic activities of the RNA-binding protein AUF1 -- Oncogenic consequences of dysregulated translation initiation -- The mTOR complexes: coordinating metabolism and translation -- Therapeutic potential of inhibiting mTOR signaling in neoplasia -- Roles of microRNAs in hematologic malignancies -- Long noncoding RNAs in inflammation, cancer, and in cancer therapy -- The epitranscriptome and cancer -- miRNA-based therapeutic strategies. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
"The roles of gene transcription in cancer have long been appreciated. However, posttranscriptional processes also contribute significantly to alterations in gene expression that lead to tumor initiation, formation, and progression. We have known for decades that alterations in the expression of key genes, such as those involved in cell proliferation, signaling, apoptosis, and immune responses, are major molecular events in cancer. This book presents our current understanding of selected posttranscriptional control mechanisms and the RNAs that they regulate. Each chapter provides an overview of a specific RNA-directed regulatory system and the RNA/protein factors involved, then discusses major findings in the field and their relationships to the development and/or treatment of cancer and associated diseases. Future questions serve to address "where do we go from here" and stimulate the reader's thinking about these important problems. This compendium of chapters from experts in the field is essential reading for anyone interested in the myriad ways that RNAs contribute to tumorigenesis: from graduate students, researchers, and clinical scientists interested in mRNA processing and translation, RNA-binding proteins that promote turnover/stability of specific mRNAs, how small noncoding RNAs control inflammation and signaling, roles of the epitranscriptome, and future and emerging RNA-based, anti-tumor therapeutics"-- |
| Assigning source |
Publisher's website. |
| 538 ## - SYSTEM DETAILS NOTE |
|---|
| System details note |
Mode of access: World Wide Web. |
| 538 ## - SYSTEM DETAILS NOTE |
|---|
| System details note |
System requirements: Adobe Acrobat Reader. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Cancer |
| General subdivision |
Genetic aspects. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Catalytic RNA. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Human genetics. |
| 655 #0 - INDEX TERM--GENRE/FORM |
|---|
| Genre/form data or focus term |
Electronic books. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Brewer, Gary |
| Fuller form of name |
(Gary A.) |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Wilson, Gerald M. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
<a href="https://www.worldscientific.com/worldscibooks/10.1142/12595#t=toc">https://www.worldscientific.com/worldscibooks/10.1142/12595#t=toc</a> |
| Public note |
Access to full text is restricted to subscribers. |